Acid-Resistant Gelatin Capsules — Manufacturer

Acid-Resistant Gelatin Capsules — Manufacturer

Introduction: Protecting Active Ingredients Through the Stomach

In the pharmaceutical and nutraceutical industries, many active ingredients are sensitive to stomach acid or are intended for targeted release in the intestines. Standard gelatin capsules dissolve quickly in the stomach, which can destroy acid-sensitive compounds or reduce their bioavailability.

Acid-resistant gelatin capsules are the solution. These specialized capsules are designed to withstand acidic gastric conditions and release their contents only when they reach the more neutral pH of the intestines.

At Medico Merim, we manufacture high-quality acid-resistant hard gelatin capsules in our GMP-certified facilities in Türkiye. Our capsules combine reliable performance, advanced enteric protection, and pharmaceutical-grade quality to help brands deliver targeted and effective formulations.


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Description

Why Acid-Resistant Capsules Are Essential

Protecting Acid-Sensitive Ingredients

Acid can degrade or inactivate many bioactives, including probiotics, enzymes, certain vitamins, and peptide-based drugs. Acid-resistant capsules shield these ingredients from stomach acid, preserving their potency.

Enabling Targeted Delivery

By delaying disintegration until the capsule reaches the intestine, acid-resistant capsules ensure that active compounds are released where they can be most effectively absorbed. This improves therapeutic outcomes and reduces side effects.

Expanding Product Possibilities

These capsules make it possible to formulate products that would otherwise be unsuitable for oral delivery. They are ideal for innovative nutraceuticals and pharmaceutical formulations.


Medico Merim — Your Trusted Manufacturer

Medico Merim is a specialized manufacturer of pharmaceutical-grade hard gelatin capsules. Based in Türkiye, we serve pharmaceutical, nutraceutical, and dietary supplement companies worldwide with reliable, high-performance capsule solutions.

GMP-Certified Production Facilities

Our acid-resistant capsules are produced in GMP-compliant plants under cleanroom conditions. Each stage — from raw material sourcing to final packaging — follows validated procedures and strict quality controls.

High-Quality Raw Materials

We use only pharmaceutical-grade, BSE/TSE-free gelatin combined with specialized enteric excipients to ensure robust acid resistance and predictable disintegration profiles.

Full Documentation Support

Each batch is supplied with:

  • Certificate of Analysis (COA)

  • Acid resistance and disintegration test reports

  • Stability and compatibility data

  • Halal and Kosher certifications upon request

  • ISO-compliant production records


Technical Specifications

  • Sizes: 000, 00, 0, 1, 2, 3, 4

  • Acid resistance: withstands pH < 2.0 for at least 2 hours

  • Disintegration: releases content in pH > 6.0 (intestinal conditions)

  • Moisture content: 13–16%

  • Shelf life: 3–5 years under recommended conditions

  • Packaging: Bulk pharmaceutical-grade containers with protective liners

  • Compatible with: powders, granules, pellets, micro-tablets

Medico Merim acid-resistant capsules are designed for smooth operation on high-speed encapsulation machines and for stable performance during global distribution.


Ideal Applications

Acid-resistant gelatin capsules are the preferred solution for formulations requiring protection from gastric acid or delayed release:

  • Probiotics and live microbial products

  • Digestive enzymes

  • Peptide and protein-based drugs

  • Vitamins sensitive to acid (such as B12, folate)

  • Botanical extracts degraded by stomach acid

  • Products designed for colonic or intestinal delivery

They are especially useful in clinical trials and export markets where regulatory standards demand documented acid resistance.


Customization Options

Medico Merim offers full customization capabilities so you can align your acid-resistant capsules with your brand identity:

  • Capsule sizes: 000 to 4

  • Colors: white, transparent, colored, two-tone, metallic, pearl

  • Custom printing: logo, product codes, brand name

  • Surface finishes: glossy, matte, pearl

  • Tailored release profiles and disintegration times

This allows you to combine targeted functionality with a distinctive, professional appearance.


Why Choose Medico Merim

Partnering with Medico Merim for acid-resistant capsules provides significant advantages:

  • Specialized manufacturer of pharmaceutical-grade targeted-release capsules

  • Proven enteric protection technology

  • High production capacity and consistent global supply

  • Flexible minimum order quantities

  • Fast lead times and efficient export logistics from Türkiye

  • Comprehensive documentation and regulatory support

  • Dedicated technical and commercial assistance

We are more than a supplier — we are your long-term manufacturing partner focused on helping you deliver innovative and effective products.


Quality and Safety Commitment

Quality is at the core of Medico Merim’s operations. We maintain strict quality control at every production stage, including raw material testing, in-process checks, and final product verification.

Our facilities operate under GMP-certified cleanroom conditions, and our team receives continuous training to ensure regulatory compliance. This guarantees that every acid-resistant capsule meets the highest global standards.


Ethical and Sustainable Manufacturing

Medico Merim is committed to ethical sourcing and sustainable practices. We use only certified gelatin from audited suppliers who follow strict animal welfare and traceability standards. We also focus on reducing waste and energy use in our manufacturing processes.


Building Long-Term Partnerships

We believe in building strong, collaborative relationships with our clients. Our team works closely with your R&D, production, and procurement departments to develop capsule solutions tailored to your exact needs.

Our responsive communication, consistent supply, and full documentation support your brand from concept to market launch and beyond.


Conclusion: Delivering Protection and Precision

Acid-resistant gelatin capsules are essential for protecting acid-sensitive ingredients, ensuring targeted intestinal delivery, and enabling advanced oral formulations. They expand product possibilities and improve therapeutic outcomes.

As a trusted manufacturer, Medico Merim combines advanced enteric technology, pharmaceutical expertise, and GMP-certified production to deliver acid-resistant capsules that meet the highest international standards.

Protect your formulations — choose Acid-Resistant Gelatin Capsules from Medico Merim

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