Delayed-Release Gelatin Capsules — Manufacturer

Delayed-Release Gelatin Capsules — Manufacturer

Introduction: Precision Timing for Maximum Effectiveness

In modern pharmaceutical and nutraceutical industries, when a drug releases can be just as important as how much releases. Some active ingredients are ineffective or degraded in the stomach and must reach the intestines intact to deliver their therapeutic effect.

Delayed-release gelatin capsules are designed to do exactly that. They are specially engineered to resist dissolution in the acidic gastric environment and release their contents only after passing into the more neutral pH conditions of the intestines.

At Medico Merim, we manufacture high-quality delayed-release hard gelatin capsules in our GMP-certified facilities in Türkiye, enabling pharmaceutical and nutraceutical companies worldwide to achieve controlled, targeted drug delivery.

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Description

Why Delayed-Release Capsules Are Essential

Protection from Stomach Acid

Many active ingredients — such as probiotics, enzymes, and certain vitamins — are destroyed or inactivated by stomach acid. Delayed-release capsules protect them until they reach the intestines.

Controlled and Targeted Delivery

Delayed-release technology ensures that ingredients are released only in the desired section of the gastrointestinal tract, improving absorption and therapeutic outcomes while reducing side effects.

Improved Patient Compliance

By minimizing gastrointestinal irritation and side effects, delayed-release capsules improve patient comfort and increase adherence to treatment regimens.


Medico Merim — Your Trusted Manufacturer

Medico Merim is a specialized manufacturer of pharmaceutical-grade hard gelatin capsules. We supply delayed-release capsules to pharmaceutical, nutraceutical, and dietary supplement companies worldwide, combining advanced technology, consistent quality, and dependable delivery.

GMP-Certified Facilities

All production takes place in our GMP-compliant cleanroom facilities. Every stage — from raw material sourcing to final packaging — follows validated procedures and strict quality protocols to ensure full regulatory compliance.

High-Quality Raw Materials

We use only BSE/TSE-free, pharmaceutical-grade gelatin combined with enteric or pH-sensitive excipients that allow controlled release profiles. This ensures both safety and functionality.

Complete Documentation

Each batch is delivered with:

  • Certificate of Analysis (COA)

  • Delayed-release dissolution test reports

  • Stability and compatibility data

  • Halal and Kosher certifications upon request

  • ISO-compliant production records


Technical Specifications

  • Sizes available: 000, 00, 0, 1, 2, 3, 4

  • Acid resistance: withstanding pH < 2.0 for at least 2 hours

  • Release profile: begins at pH > 6.0 (intestinal conditions)

  • Moisture content: 13–16%

  • Shelf life: 3–5 years under recommended conditions

  • Packaging: Bulk pharmaceutical-grade containers with protective liners

  • Compatible with: powders, granules, pellets, micro-tablets

These capsules are designed for smooth operation on high-speed filling equipment and for reliable performance in both domestic and export markets.


Applications and Industries

Delayed-release gelatin capsules are ideal for:

  • Probiotics and live microbial supplements

  • Enzyme preparations

  • Botanical extracts sensitive to gastric acid

  • Vitamins and minerals requiring intestinal release

  • Peptide- or protein-based drugs

  • Clinical trials for enteric-targeted formulations

They are especially valuable for products targeting intestinal absorption or colon-specific delivery.


Customization Options

Medico Merim offers full customization to align delayed-release capsules with your brand and product needs:

  • Capsule sizes: 000 to 4

  • Colors: white, transparent, colored, two-tone, pearl, metallic

  • Custom printing: logo, product codes, brand name

  • Surface finishes: glossy, matte, pearl

  • Tailored release profiles to match your active ingredients

This ensures your capsules are both functionally optimized and visually branded.


Why Choose Medico Merim

Working with Medico Merim provides numerous advantages:

  • Specialized manufacturer of pharmaceutical-grade delayed-release capsules

  • Advanced enteric technology for precise release profiles

  • High production capacity and consistent global supply

  • Flexible minimum order quantities

  • Fast lead times and efficient export logistics from Türkiye

  • Comprehensive regulatory and technical documentation

  • Dedicated support from concept to delivery

We are more than a supplier — we are your long-term manufacturing partner, focused on safety, performance, and product success.


Quality and Safety Commitment

At Medico Merim, quality is our foundation. We apply strict quality control at every stage, from raw material testing to final product inspection.

Our facilities operate under GMP-certified cleanroom conditions, and our staff receives continuous training to ensure compliance with international pharmacopoeia standards. This guarantees every delayed-release capsule is safe, consistent, and effective.


Ethical and Sustainable Manufacturing

We prioritize sustainability and ethical sourcing. Our gelatin is obtained from certified suppliers who follow strict animal welfare and traceability standards. We also focus on energy efficiency and waste reduction throughout our operations.


Building Long-Term Partnerships

Medico Merim values strong, lasting partnerships. We work closely with your R&D, production, and procurement teams to develop capsule solutions tailored to your exact specifications.

Our responsive communication, reliable delivery, and complete documentation support your business from concept to international market launch.


Conclusion: Precision Where It Matters Most

Delayed-release gelatin capsules enable targeted delivery of active ingredients where they are needed most — beyond the stomach, in the intestines. They improve bioavailability, reduce side effects, and unlock new formulation possibilities.

As a trusted manufacturer, Medico Merim combines advanced enteric technology, pharmaceutical expertise, and GMP-certified production to deliver delayed-release capsules that meet the highest international standards.

Deliver precision and protection — choose Delayed-Release Gelatin Capsules from Medico Merim

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